Antifertility Effect of 3-Oxo-4-Androstene-17β Carboxylic Acid in Male Mice
نویسندگان
چکیده
منابع مشابه
3β-Hydroxyfriedelan-17β-carboxylic acid
The title compound, C(30)H(50)O(3), which was isolated from a marine endophytic fungus, is a new friedelan derivative. The mol-ecule contains five six-membered rings, which exhibit boat (ring A), distorted boat (ring B) and chair (rings C-E) conformations. The crystal structure is stabilized by inter-molecular O-H⋯O hydrogen bonds, which link neighbouring mol-ecules into 12-membered rings.
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The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo-propyl-6-fluoro-4-oxo-7-(1-piperazin-yl)-1,4-dihydro-quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter-molecular C-H⋯O hydrogen bonds together with π-π electron ring inter-actions [centroid-centroid separations between quinoline rings of 3.5864 (11) and 3.9339 (13) Å]. A strong intra-molecu...
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There are two independent mol-ecules in the asymmetric unit of the title compound, C(12)H(12)N(2)O(3)S. With the exception of the methyl-ene groups, a mean plane fitted through all non-H atoms of each mol-ecule has an r.m.s. deviation of 0.035 Å for one mol-ecule and 0.120 Å for the second. In one of the independent mol-ecules, the methyl-ene groups was refined using a disorder model with an oc...
متن کاملDesign, synthesis and anti-HIV integrase evaluation of 4-oxo-4H-quinolizine-3-carboxylic acid derivatives.
4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by (1)H-NMR, (13)C- NMR, IR and ESI (or HRMS) spectra. Compounds were screened for possible HIV integrase inhibitory activity.
متن کامل(2S,4S)-3-Acryloyl-6-oxo-2-phenylperhydropyrimidine-4-carboxylic acid
In the title compound, C(14)H(14)N(2)O(4), the central six-membered ring adopts a twisted boat conformation with the phenyl substituent occupying an orthogonal position [dihedral angle = 86.88 (11)°]. In the crystal, mol-ecules are linked by carboxylic acid-carbonyl O-H⋯O and amide-carbonyl N-H⋯O hydrogen bonds, forming a three-dimensional network.
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ژورنال
عنوان ژورنال: Archives of Andrology
سال: 1979
ISSN: 0148-5016
DOI: 10.3109/01485017908987310